Everything About the Success Rate of Pregnancy with Donor Eggs

Currently, infertility treatment using donor eggs is one of the modern methods that increases the probability of pregnancy to over 85 to 90 percent. This method has received significant attention in Iran and many countries worldwide and is performed in numerous infertility treatment clinics. This method is carried out in two ways: using fresh eggs or frozen eggs, each having its own specific features. Furthermore, the success rate of this method depends on various factors. Join us to fully familiarize yourself with this topic.

What is Egg Donation and Why is it Used?

Egg donation is used when an infertile woman does not have high-quality and fertile eggs. It may also be used if the woman does not have a suitable ovarian reserve due to various reasons, such as advanced age. In this case, eggs are used voluntarily from young and healthy women. After receiving the egg, laboratory fertilization is performed with the man's sperm (the infertile woman's husband), and after embryo formation, it is transferred to the woman's uterus. Volunteer women are typically between 20 and 30 years old and are in complete physical and psychological health.



Fresh or Frozen Eggs?

As mentioned in the introduction, two methods are used for pregnancy with donor eggs: fresh eggs and frozen eggs. A fresh egg is one that enters the treatment process immediately after retrieval, while a frozen egg is one that has been cryopreserved using rapid freezing technology for use at another suitable time.

Each of the above methods has its specific characteristics. For example, fresh eggs tend to have higher quality and have not undergone rapid freezing. There is a greater possibility of repeated transfers for these eggs. However, one of the disadvantages of this method is coordinating the cycles of the donor and the recipient. This method is more expensive and usually more complex than using frozen eggs. In contrast, using frozen eggs offers greater time flexibility and lower cost. Currently, this method is very popular among infertile couples. The technology for freezing and thawing eggs has advanced significantly, and the success rate of this method does not differ significantly compared to fresh eggs.



Factors Affecting the Success Rate of Egg Donation

Successful pregnancy using donor eggs depends on various factors:

• The quality of the donor egg is the most important factor influencing the success of pregnancy and delivery. The physical and genetic health of the donor woman is the first issue that is carefully considered and tested in treatment clinics.
• The recipient woman must also have a healthy and suitable uterine status for embryo implantation, healthy endometrium, and appropriate hormonal conditions. Sometimes the egg quality is very high, and a high-quality embryo is produced, but the recipient woman's uterus is not suitable or strong.
• Another important point is sperm quality. In addition to high egg quality, the man's sperm must also have suitable quality and fertility.
• The experience and expertise of the treatment staff and the clinic's equipment will undoubtedly have a very significant and direct impact on the success rate of this treatment method.
• The infertile couple must also choose between fresh and frozen eggs after a comprehensive consultation regarding the advantages and disadvantages of each.

What is the Success Rate of Pregnancy with Donor Eggs?

As mentioned above, the success rate of pregnancy with donor eggs depends on various factors. The degree of this success varies based on the combination of these factors. Before discussing the percentage of success of this treatment method, we must understand the difference between the success rate per cycle and the cumulative success rate. The success rate per cycle is the rate of success in that single transfer stage. If the procedure is not successful in the first stage, this treatment process will be performed two to three more times. The success rate across all these stages is called the cumulative success rate.

According to global statistics in 2022, the success rate per cycle for fresh eggs is 38.7 percent and for frozen eggs is 38.9 percent. This means the success rate of both types of eggs does not differ significantly. However, you should not worry about these numbers. Statistics show that the cumulative success rate with the donor egg method is between 80 and 90 percent. Therefore, even if you are not successful in the first stage, the probability of success in subsequent cycles is very high.

Read more: IVF with Donor Eggs

Are There Age Restrictions for Using Donor Eggs?

One of the advantages and superiorities of pregnancy using donor eggs is that women over 40 can also become pregnant using young eggs. In this method, since the fertilized egg is taken from another woman, the age of the recipient does not create a specific limitation for pregnancy. Therefore, even at an advanced age, the probability of miscarriage, genetic, and chromosomal problems will decrease. Of course, other issues such as uterine incompatibility and other gynecological problems in older women must also be considered. These issues are monitored and controllable under the supervision of specialized medical staff.



Summary

The use of donor eggs is one of the successful methods in the field of infertility treatment. This treatment method is performed in two ways: using frozen and fresh eggs. The cumulative success rate of this treatment method is very high, over 80 percent. However, the degree of this success depends on various factors such as the quality of the donor egg, the recipient woman's physical condition and uterus, sperm quality, the knowledge and expertise of the treatment staff, and other factors.

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Frequently Asked Questions

Is the chance of pregnancy with frozen eggs lower?

Perhaps it was in the past, but currently, the use of advanced technologies in freezing and thawing eggs has made the success rate of this method similar to that of fresh eggs.

What does cumulative pregnancy success rate mean?

After artificial fertilization, the embryo is transferred to the recipient woman's uterus. If the procedure is not successful in the first stage, it will be done two to three more times. The success rate over the entirety of these stages is called cumulative success.

What is the cumulative success rate of pregnancy with donor eggs?

In general and cumulatively, the success rate of this method is very high, exceeding 80 percent.

Is the cost of fresh and frozen donor eggs the same?

No, frozen eggs will cost less because they do not require time coordination and have less complexity.

What factors does the success rate of pregnancy with donor eggs depend on?

Various factors such as egg quality, the recipient woman's uterine conditions, sperm quality, and the knowledge and expertise of the treatment staff will be influential.